Sialylated core 1 O-glycans influence the sorting of Pmel17/gp100 and determine its capacity to form fibrils.

Abstract

Pmel17 is a melanocyte/melanoma-specific protein that is essential for the maturation of melanosomes to form mature, fibrillar, and pigmented organelles. Recently, we reported that the less glycosylated form of Pmel17 (termed iPmel17) is sorted via the plasma membrane in a manner distinct from mature Pmel17 (termed mPmel17), which is sorted directly to… (More)

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Cite this paper

@article{Valencia2007SialylatedC1, title={Sialylated core 1 O-glycans influence the sorting of Pmel17/gp100 and determine its capacity to form fibrils.}, author={Julio C. Valencia and François Rouzaud and Sylvain Julien and Kevin G Chen and Thierry Passeron and Yuji Yamaguchi and Mones S. Abu-Asab and Maria G Tsokos and Gertrude E Costin and Hiroshi Yamaguchi and Lisa M. Miller Jenkins and Kunio Nagashima and Ettore Appella and Vincent J. Hearing}, journal={The Journal of biological chemistry}, year={2007}, volume={282 15}, pages={11266-80} }