Sialomucin complex in the rat respiratory tract: a model for its role in epithelial protection.

@article{McNeer1998SialomucinCI,
  title={Sialomucin complex in the rat respiratory tract: a model for its role in epithelial protection.},
  author={Richard McNeer and Dingde Huang and Nevis L. Fregien and Kermit L. Carraway},
  journal={The Biochemical journal},
  year={1998},
  volume={330 ( Pt 2)},
  pages={
          737-44
        }
}
The pulmonary epithelium has a multitude of specialized functions, which depend on regulated growth and differentiation of several cell types. One such function is the synthesis and secretion of mucins, which offer the epithelium protection from and a means for removal of noxious environmental factors. Sialomucin complex (SMC) is a heterodimeric glycoprotein consisting of a mucin subunit (ASGP-1, ascites sialoglycoprotein-1) and a transmembrane protein (ASGP-2) with two epidermal-growth-factor… CONTINUE READING
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