Sialic acid is a marker of lung injury following lower extremities ischemia/reperfusion.

@article{Berkan2004SialicAI,
  title={Sialic acid is a marker of lung injury following lower extremities ischemia/reperfusion.},
  author={{\"O}cal Berkan and Mehmet Kamil G{\"o}l and Serhat Içağasioğlu and O Cetnkaya and Esin Atalan Yildiz and Kasim Doğan and Ilhan G{\"u}nay},
  journal={European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery},
  year={2004},
  volume={27 5},
  pages={
          553-8
        }
}
OBJECTIVE This study tests whether sialic acid is a mediator of the lung injury following lower extremity ischemia/reperfusion (I/R). Design. Prospective randomised study. MATERIALS AND METHODS Thirty-one Sprague-Dawley rats were randomised into four groups: group 1, aorta was exposed but not clamped; group 2, aorta clamped for 3 h, followed by 1 h of reperfusion; group 3, 50 mg/kg pentoxifylline administrated before the aorta was clamped; and group 4, 1 mg/kg dexametasone administrated… CONTINUE READING
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