Siah-1b is a direct transcriptional target of p53: identification of the functional p53 responsive element in the siah-1b promoter.

Abstract

Siah proteins are E3 ubiquitin ligases. They are homologues of the Drosophila seven in absentia (Sina), a protein required for the R7 photoreceptor development. We have previously found that the expression of human siah-1 and its mouse homologue siah-1b are induced by p53 during apoptosis and tumor reversion. So far, no evidence that the siah-1b gene is a… (More)

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@article{Fiucci2004Siah1bIA, title={Siah-1b is a direct transcriptional target of p53: identification of the functional p53 responsive element in the siah-1b promoter.}, author={Giusy Fiucci and S{\'e}verine Beaucourt and Dominique Duflaut and Alexandra Lespagnol and Pamela Stumptner-Cuvelette and Anne G{\'e}ant and Gilles Buchwalter and Marcel Tuynder and Laurent Susini and J Lassalle and Christine Wasylyk and Bohdan Wasylyk and Moshe Oren and Robert B Amson and Adam Telerman}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2004}, volume={101 10}, pages={3510-5} }