Shugoshin: guardian spirit at the centromere.

@article{Watanabe2005ShugoshinGS,
  title={Shugoshin: guardian spirit at the centromere.},
  author={Yoshinori Watanabe},
  journal={Current opinion in cell biology},
  year={2005},
  volume={17 6},
  pages={
          590-5
        }
}
A recently emerging protein family, shugoshin, plays a crucial role in the centromeric protection of cohesin, which is responsible for sister chromatid cohesion. This is especially important at the first meiotic division, where cohesin is cleaved by separase only along chromosome arms while the centromeric cohesin must be preserved. In vertebrate cells, arm cohesion is largely lost during prophase and prometaphase in order to facilitate sister chromatid resolution, whereas centromeric cohesion… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 69 CITATIONS, ESTIMATED 58% COVERAGE

126 Citations

01020'08'11'14'17
Citations per Year
Semantic Scholar estimates that this publication has 126 citations based on the available data.

See our FAQ for additional information.

Similar Papers

Loading similar papers…