Shuffling the Deck Anew: How NR3 Tweaks NMDA Receptor Function

@article{Cavara2008ShufflingTD,
  title={Shuffling the Deck Anew: How NR3 Tweaks NMDA Receptor Function},
  author={Nora A. Cavara and Michael Hollmann},
  journal={Molecular Neurobiology},
  year={2008},
  volume={38},
  pages={16-26}
}
The N-methyl-d-aspartate (NMDA) receptors are the most complex members in the family of ionotropic glutamate receptors. They are involved in long-term potentiation and underlie higher cognitive functions like memory formation and learning. On the other hand, overstimulation of NMDA receptors (NMDARs), leading to a massive influx of Ca2+ ions into the cell, is linked to neurodegenerative disorders such as for example Huntington’s disease and epilepsy. NMDARs are generally considered to be… CONTINUE READING

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