Should we abandon quinine plus antibiotic for treating uncomplicated falciparum malaria? A systematic review and meta-analysis of randomized controlled trials

@article{Song2015ShouldWA,
  title={Should we abandon quinine plus antibiotic for treating uncomplicated falciparum malaria? A systematic review and meta-analysis of randomized controlled trials},
  author={Tianzhang Song and Jintao Chen and Lilin Huang and Wenjia Gan and Hongling Yin and Juan Jiang and Tailong He and Huaiqiu Huang and Xuchu Hu},
  journal={Parasitology Research},
  year={2015},
  volume={115},
  pages={903-912}
}
In this study, we compared the efficacies and adverse effects of quinine plus antibiotics and other anti-malaria drugs on treating uncomplicated falciparum malaria. By systematically searching the major databases PubMed, Embase, and the Cochrane Library, 14 randomized controlled trials (RCTs) including 1996 cases were identified. Then, we performed a systematic review and cumulative meta-analysis on these data. The primary outcome of these treatments was parasite failure at day 28. There was no… Expand
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