Should vitamin K antagonist therapy be started simultaneously with parenteral anticoagulation: a meta-analysis?

@article{Qayyum2012ShouldVK,
  title={Should vitamin K antagonist therapy be started simultaneously with parenteral anticoagulation: a meta-analysis?},
  author={Fareeha Qayyum and Anne Holbrook and Jason Lam and Michael J. Kovacs and Sam Schulman},
  journal={Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis},
  year={2012},
  volume={23 8},
  pages={705-13}
}
For patients with an acute episode of venous thromboembolism (VTE), the optimal starting time of long-term therapy with vitamin K antagonists (VKA) and how much overlap should occur with heparin are unclear and the current guidelines and practice are not based on high-quality data. The objective of this study was to perform a meta-analysis on the evidence… CONTINUE READING