Should the hot-plate test be reincarnated?

Abstract

To the Editor: There is growing concern regarding the failure of translational research to produce effective, long-term treatments of chronic pain. Most of the criticism has targeted the validity and clinical relevance of laboratory animal models of pain Because preclinical studies cannot benefit from self-report— a key component of human pain studies—we… (More)
DOI: 10.1016/j.jpain.2011.05.003

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