Should statins be given routinely before carotid endarterectomy?

  title={Should statins be given routinely before carotid endarterectomy?},
  author={Bruce A. Perler},
  journal={Perspectives in vascular surgery and endovascular therapy},
  volume={19 3},
  • Bruce A. Perler
  • Published 2007 in
    Perspectives in vascular surgery and endovascular…
Statins belong to a class of drugs known to inhibit 3-hydroxy 3-methylglutaryl coenzyme A (HMG CoA) reductase, and block hepatic cholesterol synthesis. Statins have been found to be highly effective in primary and secondary stroke prevention among medically managed patients with cardiovascular disease, and it appears that this benefit is largely owing to the non-cholesterol-lowering, so called pleiotropic, effects of statins. Over the past decade, agents such as beta-blockers, aspirin, or other… CONTINUE READING