Should methotrexate be discontinued before elective orthopedic surgery in patients with rheumatoid arthritis?

@article{Bridges1991ShouldMB,
  title={Should methotrexate be discontinued before elective orthopedic surgery in patients with rheumatoid arthritis?},
  author={S. Louis Bridges and A L{\'o}pez-M{\'e}ndez and K. Huub Han and I C Tracy and Graciela S Alarc{\'o}n},
  journal={The Journal of rheumatology},
  year={1991},
  volume={18 7},
  pages={984-8}
}
To determine if methotrexate (MTX) contributes to early postoperative complications, we studied 38 patients with rheumatoid arthritis (RA) who underwent elective orthopedic surgery. There were 4 complications of prosthetic joint infection or wound dehiscence or infection among 19 procedures performed on patients who continued MTX until less than 4 weeks before surgery, compared to no complications among 34 procedures performed on patients who discontinued MTX 4 weeks before surgery or who were… CONTINUE READING
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