Should heparin-binding protein levels be routinely monitored in patients with severe sepsis and septic shock?

Abstract

Heparin-binding protein (HBP), also known as azurocidin, has multiple functions in the inflammatory process, especially during severe infections. Beside its antimicrobial properties, HBP may induce vascular leakage leading to extravascular efflux, which is an important pathophysiologic event in the development of septic shock. Not surprisingly, high HBP… (More)
DOI: 10.1186/cc11379

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