Should Celecoxib Be Contraindicated in Patients Who Are Allergic to Sulfonamides?

@article{Knowles2001ShouldCB,
  title={Should Celecoxib Be Contraindicated in Patients Who Are Allergic to Sulfonamides?},
  author={Sandra R. Knowles and Lori E. Shapiro and Neil H. Shear},
  journal={Drug Safety},
  year={2001},
  volume={24},
  pages={239-247}
}
Celecoxib, a selective cyclo-oxygenase-2 inhibitor, is a diaryl-substituted pyrazole derivative containing a sulfonamide substituent. Because of this structural component, celecoxib is contraindicated for use in patients who have demonstrated allergic reactions to sulfonamides. However, there is a lack of data demonstrating cross-reactivity among sulfonamide medications.A sulfonamide is any compound with an SO2NH2 moiety. The major difference between sulfonamide antimicrobials and other… 
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