Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.

@article{Pieragostino2013ShotgunPR,
  title={Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma na{\"i}ve to therapy.},
  author={Damiana Pieragostino and Luca Agnifili and Vincenzo Fasanella and Simona D'Aguanno and Rodolfo Mastropasqua and Carmine di Ilio and Paolo Sacchetta and Andrea Urbani and Piero Del Boccio},
  journal={Molecular bioSystems},
  year={2013},
  volume={9 6},
  pages={1108-16}
}
Primary open angle glaucoma (POAG) is one of the main causes of irreversible blindness worldwide. The pathogenesis of POAG is still unclear. Alteration and sclerosis of trabecular meshwork with changes in aqueous humor molecular composition seem to play the key role. Increased intraocular pressure is widely known to be the main risk factor for the onset and progression of the disease. Unfortunately, the early diagnosis of POAG still remains the main challenge. In order to provide insight into… CONTINUE READING
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