Shotgun mass spec goes independent

Abstract

trap3. This new approach offers important advantages for both protein identification and quantification in shotgun analyses3. The principle of shotgun analysis is to first ‘spread out’ peptides in complex mixtures by multidimensional chromatographic separation. Tandem MS instruments then acquire peptide MS/MS spectra, which encode the peptide sequences… (More)
DOI: 10.1038/nmeth1004-16

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