Shortstop Recruits EB1/APC1 and Promotes Microtubule Assembly at the Muscle-Tendon Junction

@article{Subramanian2003ShortstopRE,
  title={Shortstop Recruits EB1/APC1 and Promotes Microtubule Assembly at the Muscle-Tendon Junction},
  author={Arul Subramanian and Andreas Prokop and Misato Yamamoto and Kaoru Sugimura and Tadashi Uemura and Joerg Betschinger and Juergen A. Knoblich and Talila Volk},
  journal={Current Biology},
  year={2003},
  volume={13},
  pages={1086-1095}
}
BACKGROUND Shot (previously named Kakapo), is a Drosophila Plakin family member containing both Actin binding and microtubule binding domains. In Drosophila, it is required for a wide range of processes, including axon extension, dendrite formation, axonal terminal arborization at the neuromuscular junction, tendon cell development, and adhesion of wing epithelium. RESULTS To address how Shot exerts its activity at the molecular level, we investigated the molecular interactions of Shot with… CONTINUE READING