Shortened cytoplasmic domain affects intracellular transport but not nuclear localization of a viral glycoprotein.

@article{Raviprakash1990ShortenedCD,
  title={Shortened cytoplasmic domain affects intracellular transport but not nuclear localization of a viral glycoprotein.},
  author={K Raviprakash and L Rasile and Kakoli Ghosh and Hara P. Ghosh},
  journal={The Journal of biological chemistry},
  year={1990},
  volume={265 3},
  pages={1777-82}
}
Herpes simplex virus (HSV) buds from the inner nuclear membrane of the infected cells. The glycoprotein gB-1 of HSV contains a stretch of 69 hydrophobic amino acids near the COOH terminus and a 109-amino acid cytoplasmic domain. By oligonucleotide-directed mutagenesis, five gB-1 mutants were constructed which either lack a cytoplasmic tail or contained 3, 6… CONTINUE READING