Shortage of human intravenous immunoglobulin—reasons and possible solutions

  title={Shortage of human intravenous immunoglobulin—reasons and possible solutions},
  author={Jagadeesh Bayry and Michel Daniel Kazatchkine and Srini V Kaveri},
  journal={Nature Clinical Practice Neurology},
Intravenous immunoglobulin (IVIg) is a therapeutic preparation of normal human polyclonal IgG obtained by pooling plasma from a large number of healthy blood donors. Initially used as replacement therapy in primary and secondary immune deficiencies, IVIg is also widely used for the treatment of a number of autoimmune and systemic inflammatory diseases, including many that affect the nervous system, such as Guillain– Barré syndrome and multifocal motor neuropathy.1 IVIg has become the main… CONTINUE READING
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Properties of a new intravenous immunoglobulin (IGIV-C, 10%) produced by virus inactivation with caprylate and column chromatography

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