Short-term treadmill running in the rat: what kind of stressor is it?

  title={Short-term treadmill running in the rat: what kind of stressor is it?},
  author={David Brown and Micah S. Johnson and C. J. Armstrong and Joshua M. Lynch and Nicholas M. Caruso and Lindsay B Ehlers and Monika Fleshner and Robert L Spencer and Russell Moore},
  journal={Journal of applied physiology},
  volume={103 6},
The use of short-term (1-5 days) treadmill running is becoming increasingly common as a model to study physiological adaptations following the exercise. Although the beneficial effects of acute exercise seem clear, a paucity of data exist describing potential markers of stress in response to forced running. We subjected male and female Sprague-Dawley rats to 0, 1, 2, 5, or 10 days of treadmill running. Twenty-four to 32 h after the last bout of exercise animals were killed and examined for… CONTINUE READING


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