Short-term starvation and mitochondrial dysfunction - a possible mechanism leading to postoperative insulin resistance.

@article{Awad2009ShorttermSA,
  title={Short-term starvation and mitochondrial dysfunction - a possible mechanism leading to postoperative insulin resistance.},
  author={Sherif Awad and Dumitru Constantin-Teodosiu and Ian Macdonald and Dileep N Lobo},
  journal={Clinical nutrition},
  year={2009},
  volume={28 5},
  pages={497-509}
}
BACKGROUND Preoperative starvation results in the development of insulin resistance. Measures to attenuate the development of insulin resistance, such as preoperative carbohydrate loading, lead to clinical benefits. However, the mechanisms that underlie the development of insulin resistance during starvation and its attenuation by preoperative carbohydrate loading remain to be defined. Insulin resistance associated with type 2 diabetes and ageing has been linked to mitochondrial dysfunction… CONTINUE READING

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