Short-term oral toxicity of three biodiesels and an ultra-low sulfur diesel in male rats.

@article{Poon2009ShorttermOT,
  title={Short-term oral toxicity of three biodiesels and an ultra-low sulfur diesel in male rats.},
  author={Raymond Poon and Victor E. O. Valli and M. R. Rigden and Greg Rideout and Guillaume Pelletier},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2009},
  volume={47 7},
  pages={1416-24}
}
Male rats were administered one of three biodiesels - soy oil methyl ester (SoME-2), canola oil methyl ester (CaME-2), and methyl ester of animal frying oil (FrAME-1) at 5, 50 and 500 mg/kg, or ultra-low sulphur diesel (ULSD) at 500 mg/kg. Control was administered the vehicle (corn oil) only. After 4-week treatment, serum methanol and formic acid were unchanged or minimally elevated in all treatment groups. Mild histopathological changes in the liver were observed in animals receiving 500 mg/kg… CONTINUE READING

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