Short-term glucosamine infusion increases islet blood flow in anesthetized rats

@article{Gao2013ShorttermGI,
  title={Short-term glucosamine infusion increases islet blood flow in anesthetized rats},
  author={Xiang Gao and L. Jansson and A. Persson and M. Sandberg},
  journal={Islets},
  year={2013},
  volume={5},
  pages={201 - 206}
}
  • Xiang Gao, L. Jansson, +1 author M. Sandberg
  • Published 2013
  • Medicine
  • Islets
  • Impaired glucose tolerance and type 2 diabetes in rodents are associated with increased islet blood flow. If this is important for modulation of the endocrine function is at present unknown. We evaluated if glucosamine infusion, which induces peripheral insulin resistance and glucose intolerance, could be used to acutely increase islet blood flow. We infused anaesthetized Sprague-Dawley rats for 2 h with glucosamine (6 mg/kg body weight), in some cases followed by glucose administration. The… CONTINUE READING

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