Short-term follow-up of digital ulcers by laser speckle contrast analysis in systemic sclerosis patients.

@article{Ruaro2015ShorttermFO,
  title={Short-term follow-up of digital ulcers by laser speckle contrast analysis in systemic sclerosis patients.},
  author={Barbara Ruaro and Alberto Sulli and Vanessa H Smith and Sabrina Paolino and Carmen Pizzorni and Maurizio Cutolo},
  journal={Microvascular research},
  year={2015},
  volume={101},
  pages={82-5}
}
OBJECTIVE To monitor in systemic sclerosis (SSc) the evolution of digital ulcer (DU) status by analysing blood perfusion (BP) using laser speckle contrast analysis (LASCA). METHODS Hand BP was recorded by LASCA in twenty SSc patients with recent onset fingertip DUs before and after 10days of local/systemic treatment. Regions of interest (ROIs) to analyse BP were created al the level of ulcer, peri-ulcer, periungual and fingertip areas. Visual analogue pain scale (VAS) was also administered to… CONTINUE READING

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