Short-term exposures of rats to airborne hydrogen fluoride.

  title={Short-term exposures of rats to airborne hydrogen fluoride.},
  author={Walden E Dalbey and Bruce Dunn and Ross Bannister and Wayne C. Daughtrey and Catherine Kirwin and Frieda Reitman and Mary Wells and Jason I.E. Bruce},
  journal={Journal of toxicology and environmental health. Part A},
  volume={55 4},
A series of acute inhalation exposures was performed with airborne hydrogen fluoride (HF) to establish the concentration response for nonlethal effects in the rat. Exposures were either 2 or 10 min long; concentrations ranged from 135 to 8621 ppm. Three additional exposures (20 to 48 ppm) were performed for 60 min. A mouth-breathing (MB) model with a tracheal cannula was used in most of the exposures to maximize delivery of the HF to the lower respiratory tract. Endpoints on the day after… CONTINUE READING