Short-term environmental enrichment enhances synaptic plasticity in hippocampal slices from aged rats.

@article{Stein2016ShorttermEE,
  title={Short-term environmental enrichment enhances synaptic plasticity in hippocampal slices from aged rats.},
  author={Liana Roberts Stein and Kazuko A O'dell and Michiyo Funatsu and Charles F Zorumski and Yukitoshi Izumi},
  journal={Neuroscience},
  year={2016},
  volume={329},
  pages={294-305}
}
Age-associated changes in cognition are mirrored by impairments in cellular models of memory and learning, such as long-term potentiation (LTP) and long-term depression (LTD). In young rodents, environmental enrichment (EE) can enhance memory, alter LTP and LTD, as well as reverse cognitive deficits induced by aging. Whether short-term EE can benefit… CONTINUE READING