Short-term efficacy of the IL 6 receptor antibody tocilizumab in patients with HIV-associated multicentric Castleman disease : report of two cases

@inproceedings{Nagao2014ShorttermEO,
  title={Short-term efficacy of the IL 6 receptor antibody tocilizumab in patients with HIV-associated multicentric Castleman disease : report of two cases},
  author={Azusa Nagao and Shoko Nakazawa and Hideji Hanabusa},
  year={2014}
}
Multicentric Castleman disease (MCD) is a lymphoproliferative disorder caused by human herpesvirus 8 (HHV8) infection HIV associated MCD (HIV-MCD) presents with various clinical symptoms. Many HIV-negative MCD patients are often treated with anti-human interleukin-6 (IL6) receptor monoclonal antibodies (tocilizumab), and successful results have been reported. IL-6 plays an important role in the development of both HIV-positive and HIV-negative MCD; however, the efficacy of tocilizumab in HIV… CONTINUE READING
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