Short-term efficacy of pharmacotherapeutic interventions in osteoarthritic knee pain: A meta-analysis of randomised placebo-controlled trials.

@article{Bjordal2007ShorttermEO,
  title={Short-term efficacy of pharmacotherapeutic interventions in osteoarthritic knee pain: A meta-analysis of randomised placebo-controlled trials.},
  author={Jan Magnus Bjordal and Atle Klovning and Anne Elisabeth Ljunggren and Lars Sl\ordal},
  journal={European journal of pain},
  year={2007},
  volume={11 2},
  pages={125-38}
}
BACKGROUND Pain is the most debilitating symptom in osteoarthritis of the knee (OAK). AIM AND METHODS To determine the short-term pain-relieving effects of seven commonly used pharmacological agents for OAK pain by performing a systematic review of randomised placebo-controlled trials. RESULTS In total, 14,060 patients in 63 trials were evaluated. Opioids and oral NSAIDs therapy in patients with moderate to severe pain (mean baseline 64.3 and 72.8 mm on VAS respectively) had maximum… CONTINUE READING

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125–138 double-blind study versus placebo and celecoxib

J. M. Bjordal
European Journal of Pain • 2007

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