Short-term effects of vitamin A and antimalarial treatment on erythropoiesis in severely anemic Zanzibari preschool children.

@article{Cusick2005ShorttermEO,
  title={Short-term effects of vitamin A and antimalarial treatment on erythropoiesis in severely anemic Zanzibari preschool children.},
  author={Sarah E Cusick and James M. Tielsch and Mahdi M. Ramsan and Jape Khatib Jape and Sunil Sazawal and Robert E. Black and Rebecca J Stoltzfus},
  journal={The American journal of clinical nutrition},
  year={2005},
  volume={82 2},
  pages={406-12}
}
BACKGROUND The pathophysiology of anemia in coastal East Africa is complex. Impaired erythropoietin production is one possible mechanism. Plasmodium falciparum malaria has been found to blunt erythropoietin production, whereas vitamin A stimulates erythropoietin production in vitro. OBJECTIVE We investigated the 72-h effects of vitamin A and the antimalarial drug sulfadoxine pyramethamine (SP) on erythropoietin production in severely anemic (hemoglobin < or = 70 g/L) preschool children in… CONTINUE READING
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