Short-term effects of synthetic human parathyroid hormone-(1--34) administration on bone mineral metabolism in osteoporotic patients.

@article{Slovik1981ShorttermEO,
  title={Short-term effects of synthetic human parathyroid hormone-(1--34) administration on bone mineral metabolism in osteoporotic patients.},
  author={D. Slovik and R. Neer and J. Potts},
  journal={The Journal of clinical investigation},
  year={1981},
  volume={68 5},
  pages={
          1261-71
        }
}
Since studies in animals and humans have shown that parathyroid hormone can stimulate bone formation and increase trabecular bone, and patients with primary and secondary hyperparathyroidism may exhibit osteosclerosis, we evaluated the effect of short-term administration of human parathyroid hormone, hPTH-(1--34), in patients with osteoporosis. Six patients with osteoporosis underwent detailed studies including blood and urinary measurements of calcium, phosphate, and magnesium; 47Ca kinetic… Expand
Sequential effects of chronic human PTH (1‐84) treatment of estrogen‐deficiency osteopenia in the rat
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