Short term changes in the proteome of human cerebral organoids induced by 5-MeO-DMT

@inproceedings{Dakic2017ShortTC,
  title={Short term changes in the proteome of human cerebral organoids induced by 5-MeO-DMT},
  author={Vanja Dakic and Juliana Minardi Nascimento and Rafaela Costa Sartore and Renata de Moraes Maciel and Dr{\'a}ulio Barros de Ara{\'u}jo and Sidarta Ribeiro and Daniel Martins-de-Souza and Stevens K. Rehen},
  booktitle={Scientific Reports},
  year={2017}
}
Dimethyltryptamines are entheogenic serotonin-like molecules present in traditional Amerindian medicine recently associated with cognitive gains, antidepressant effects, and changes in brain areas related to attention. Legal restrictions and the lack of adequate experimental models have limited the understanding of how such substances impact human brain metabolism. Here we used shotgun mass spectrometry to explore proteomic differences induced by 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) on… CONTINUE READING