Short-term bed rest increases TLR4 and IL-6 expression in skeletal muscle of older adults.


Bed rest induces significant loss of leg lean mass in older adults. Systemic and tissue inflammation also accelerates skeletal muscle loss, but it is unknown whether inflammation is associated to inactivity-induced muscle atrophy in healthy older adults. We determined if short-term bed rest increases toll-like receptor 4 (TLR4) signaling and pro… (More)
DOI: 10.1152/ajpregu.00072.2013

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