Short-term antidepressant treatment and facial processing. Functional magnetic resonance imaging study.

@article{Norbury2007ShorttermAT,
  title={Short-term antidepressant treatment and facial processing. Functional magnetic resonance imaging study.},
  author={Ray Norbury and Clare E. Mackay and Philip J. Cowen and Guy M. Goodwin and Catherine J. Harmer},
  journal={The British journal of psychiatry : the journal of mental science},
  year={2007},
  volume={190},
  pages={
          531-2
        }
}
We used functional magnetic resonance imaging to investigate the effects of short-term treatment with reboxetine, a selective noradrenaline reuptake inhibitor, on emotional facial processing in healthy volunteers. Reboxetine was associated with a reduced amygdala response to fearful faces and increased activation to happy v. neutral facial expressions in the right fusiform gyrus, relative to placebo treatment and in the absence of changes in mood. Our results show that reboxetine modulates the… CONTINUE READING
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