Short-term administration of antivascular endothelial growth factor antibody in the late follicular phase delays follicular development in the rhesus monkey.

@article{Zimmermann2001ShorttermAO,
  title={Short-term administration of antivascular endothelial growth factor antibody in the late follicular phase delays follicular development in the rhesus monkey.},
  author={Ralf C. Zimmermann and Emily Xiao and Nabil Husami and Mark V. Sauer and Roger A. Lobo and Jan K. Kitajewski and Michel Ferin},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2001},
  volume={86 2},
  pages={
          768-72
        }
}
Indirect evidence in the nonhuman primate and human suggests that angiogenesis and regulators of angiogenesis such as vascular endothelial growth factor (VEGF) may play an active role in cyclic folliculogenesis. Indeed, the follicle selected for maturation and ovulation possesses a denser microvascular network, and VEGF messenger ribonucleic acid and its protein have been identified in granulosa cells of the developing follicle during the mid- and late follicular phases, with a more intense… Expand
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