Short-term administration of antivascular endothelial growth factor antibody in the late follicular phase delays follicular development in the rhesus monkey.

@article{Zimmermann2001ShorttermAO,
  title={Short-term administration of antivascular endothelial growth factor antibody in the late follicular phase delays follicular development in the rhesus monkey.},
  author={Ralf Zimmermann and Ennian Xiao and Nabil Husami and Mark V. Sauer and R. F. J. Lobo and Jan Kitajewski and Michel J Ferin},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2001},
  volume={86 2},
  pages={768-72}
}
Indirect evidence in the nonhuman primate and human suggests that angiogenesis and regulators of angiogenesis such as vascular endothelial growth factor (VEGF) may play an active role in cyclic folliculogenesis. Indeed, the follicle selected for maturation and ovulation possesses a denser microvascular network, and VEGF messenger ribonucleic acid and its protein have been identified in granulosa cells of the developing follicle during the mid- and late follicular phases, with a more intense… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 33 extracted citations

Similar Papers

Loading similar papers…