Short telomere length, lung function and chronic obstructive pulmonary disease in 46,396 individuals.

@article{Rode2013ShortTL,
  title={Short telomere length, lung function and chronic obstructive pulmonary disease in 46,396 individuals.},
  author={Line Rode and Stig Egil Bojesen and Maren Weischer and Joergen Vestbo and B\orge G. Nordestgaard},
  journal={Thorax},
  year={2013},
  volume={68 5},
  pages={429-35}
}
BACKGROUND A previous case-control study of 100 individuals found that short telomere length was associated with a 28-fold increased risk of chronic obstructive pulmonary disease (COPD). OBJECTIVES To test the hypothesis that short telomere length is associated with reduced lung function and an increased risk of COPD. METHODS Observational study of 46 396 individuals from the Danish general population. MEASUREMENTS Leucocyte telomere length and spirometry were measured. COPD was defined… CONTINUE READING
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