Short report: increased susceptibility to Plasmodium malariae in pregnant alpha(+)-thalassemic women.

@article{Mockenhaupt2001ShortRI,
  title={Short report: increased susceptibility to Plasmodium malariae in pregnant alpha(+)-thalassemic women.},
  author={Frank P Mockenhaupt and Bei Rong and Holger Till and William Nana Thompson and Ulrich Bienzle},
  journal={The American journal of tropical medicine and hygiene},
  year={2001},
  volume={64 1-2},
  pages={6-8}
}
The influence of alpha(+)-thalassemia on malaria in pregnancy was assessed in a cross-sectional study of 530 women in Ghana. Plasmodial infections, alpha(+)-thalassemia, serum levels of C-reactive protein, and antimalarial drugs in urine were determined. The alpha-globin genotypes did not correlate with the prevalence of Plasmodium falciparum-infection and parasite densities. However, Plasmodium malariae tended to be more frequent in alpha(+)-thalassemic women (P = 0.05). Excluding women with… CONTINUE READING

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