Short one-pot chemo-enzymatic synthesis of L-lysine and L-alanine diblock co-oligopeptides.


Amphiphilic diblock co-oligopeptides are interesting and functional macromolecular materials for biomedical applications because of their self-assembling properties. Here, we developed a synthesis method for diblock co-oligopeptides by using chemo-enzymatic polymerization, which was a relatively short (30 min) and efficient reaction (over 40% yield). Block… (More)
DOI: 10.1021/bm4015254


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