Short latency activation of cortex by clinically effective thalamic brain stimulation for tremor.

@article{Walker2012ShortLA,
  title={Short latency activation of cortex by clinically effective thalamic brain stimulation for tremor.},
  author={Harrison Walker and He Huang and Christopher L Gonzalez and James E Bryant and Jeffrey F. Killen and Robert C. Knowlton and Erwin B. Montgomery and Gary C. Cutter and Abidin Yildirim and Bart L Guthrie and Ray L. Watts},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={2012},
  volume={27 11},
  pages={
          1404-12
        }
}
Deep brain stimulation (DBS) relieves disabling symptoms of neurologic and psychiatric diseases when medical treatments fail, yet its therapeutic mechanism is unknown. We hypothesized that ventral intermediate (VIM) nucleus stimulation for essential tremor activates the cortex at short latencies, and that this potential is related to the suppression of tremor in the contralateral arm. We measured cortical activity with electroencephalography in 5 subjects (seven brain hemispheres) across a… CONTINUE READING
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