Short-dwell ethanol lock therapy in children is associated with increased clearance of central line-associated bloodstream infections.

@article{McGrath2011ShortdwellEL,
  title={Short-dwell ethanol lock therapy in children is associated with increased clearance of central line-associated bloodstream infections.},
  author={Eric McGrath and Ralph G Salloum and Xinguang Chen and Yifan Jiang and Kathrina Boldt-MacDonald and Cristie J Becker and Roland L Chu and Jocelyn Yu Ang},
  journal={Clinical pediatrics},
  year={2011},
  volume={50 10},
  pages={943-51}
}
BACKGROUND Central line-associated bloodstream infection (CLABSI) is a known complication of central line use. Salvage of infected central lines with ethanol lock therapy (ELT) with systemic antimicrobials may be an alternative treatment option in children. METHODS Retrospective review was performed in children with CLASBI who underwent short-dwell ELT (70% ethanol, 4- to 25-hour dwell times ≤3 days) with systemic antimicrobials from January 1, 2007 to July 15, 2009. RESULTS A total of 59… CONTINUE READING

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