Short communication: Biological and genetic characterization of HIV type 1 subtype B and nonsubtype B transmitted viruses: usefulness for vaccine candidate assessment.

@article{Cuevas2010ShortCB,
  title={Short communication: Biological and genetic characterization of HIV type 1 subtype B and nonsubtype B transmitted viruses: usefulness for vaccine candidate assessment.},
  author={Mar{\'i}a Teresa Cuevas and Aurora Fern{\'a}ndez-Garc{\'i}a and Milagros Pinilla and V Garc{\'i}a-Alvarez and Miguel Thomson and Elena Delgado and Mar{\'i}a Gonz{\'a}lez-Galeano and Celia Miralles and Esther Serrano-Bengoechea and R Ojea de Castro and Mar{\'i}a Jos{\'e} L{\'o}pez-{\'A}lvarez and Mar{\'i}a Jes{\'u}s Leza{\'u}n and Ana M S{\'a}nchez-Garc{\'i}a and M{\'o}nica S{\'a}nchez-Mart{\'i}nez and Mercedes Mu{\~n}oz-Nieto and Luc{\'i}a P{\'e}rez-{\'A}lvarez},
  journal={AIDS research and human retroviruses},
  year={2010},
  volume={26 9},
  pages={1019-25}
}
Due to the extraordinary degree of genetic diversity of HIV-1 and the structural complexity of its envelope glycoproteins, designing an effective vaccine is difficult, requiring the development of viral reagents to assess vaccine-elicited neutralizing antibodies. The aim of this study was to improve on our previously developed panel of HIV-1 strains of different genetic forms, focusing on strains from acute and recently acquired infections as the most representative of the transmitted viruses… CONTINUE READING