Short chain diol metabolism in human disease states.

  title={Short chain diol metabolism in human disease states.},
  author={Joseph P. Casazza and Byung Jun Song and Richard L. Veech},
  journal={Trends in biochemical sciences},
  volume={15 1},
Recent clinical studies have shown the presence of two short chain diols, meso-2,3-butanediol and D/L-2,3-butanediol, and in most cases 1,2-propanediol in either serum or urine collected from humans in several apparently unrelated disease states: congenital propionic and methylmalonic acidemia, premature infants, and alcoholics both in the presence and absence of ethanol. In addition 1,2-propanediol has been shown in patients during prolonged starvation, and in patients with diabetic keto… CONTINUE READING

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