Short-chain consensus alpha-neurotoxin: a synthetic 60-mer peptide with generic traits and enhanced immunogenic properties

@article{Rosa2018ShortchainCA,
  title={Short-chain consensus alpha-neurotoxin: a synthetic 60-mer peptide with generic traits and enhanced immunogenic properties},
  author={Guillermo de la Rosa and Ligia L Corrales-Garc{\'i}a and Ximena Rodriguez-Ruiz and Estuardo L{\'o}pez-Vera and Gerardo Corzo},
  journal={Amino Acids},
  year={2018},
  volume={50},
  pages={885-895}
}
The three-fingered toxin family and more precisely short-chain α-neurotoxins (also known as Type I α-neurotoxins) are crucial in defining the elapid envenomation process, but paradoxically, they are barely neutralized by current elapid snake antivenoms. This work has been focused on the primary structural identity among Type I neurotoxins in order to create… CONTINUE READING