Short- but not long-lasting treadmill running reduces allodynia and improves functional recovery after peripheral nerve injury.

@article{Cobianchi2010ShortBN,
  title={Short- but not long-lasting treadmill running reduces allodynia and improves functional recovery after peripheral nerve injury.},
  author={Stefano Cobianchi and S. Marinelli and Fulvio Florenzano and Flaminia Pavone and Siro Luvisetto},
  journal={Neuroscience},
  year={2010},
  volume={168 1},
  pages={273-87}
}
We analyzed the effects of different treadmill running protocols on the functional recovery after chronic constriction injury (CCI) of the sciatic nerve in mice. We found that a treadmill protocol of short-lasting running (1 h/d for 5 days after CCI) reduced the neuropathy-induced mechanical allodynia and normalized the weight bearing and the sciatic static index of the injured hindpaw. At difference, a treadmill protocol of long-lasting running (1 h/d for more than 5 days after CCI) was… CONTINUE READING

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