Short and tall stature: a new paradigm emerges

  title={Short and tall stature: a new paradigm emerges},
  author={Jeffrey Baron and Lars S{\"a}vendahl and Francesco De Luca and Andrew Dauber and Moshe Phillip and Jan Maarten Wit and Ola Nilsson},
  journal={Nature Reviews Endocrinology},
In the past, the growth hormone (GH)–insulin-like growth factor 1 (IGF-1) axis was often considered to be the main system that regulated childhood growth and, therefore, determined short stature and tall stature. However, findings have now revealed that the GH–IGF-1 axis is just one of many regulatory systems that control chondrogenesis in the growth plate, which is the biological process that drives height gain. Consequently, normal growth in children depends not only on GH and IGF-1 but also… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 24 times over the past 90 days. VIEW TWEETS
30 Citations
148 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 30 extracted citations


Publications referenced by this paper.
Showing 1-10 of 148 references

Similar Papers

Loading similar papers…