Short- and long-term distribution and toxicity of gold nanoparticles in the rat after a single-dose intravenous administration.


UNLABELLED Surface chemistry plays an important role in gold nanoparticles (AuNPs) stability and biocompatibility, which are crucial for their implementation into the clinical setting. We evaluated short- (30 min) and long-term (28 days) biodistribution and toxicity of ~20 nm citrate- and pentapeptide CALNN-coated AuNPs after a single intravenous injection… (More)
DOI: 10.1016/j.nano.2014.06.005