Short and long telomeres increase risk of amnestic mild cognitive impairment.

  title={Short and long telomeres increase risk of amnestic mild cognitive impairment.},
  author={Rosebud O. Roberts and Lisa A Boardman and Ruth H. Cha and V. Shane Pankratz and Ruth A. Johnson and Brooke R. Druliner and Teresa J.H. Christianson and Lewis R. Roberts and Ronald C. Petersen},
  journal={Mechanisms of ageing and development},
Peripheral blood telomere length has been associated with age-related conditions including Alzheimer's disease (AD). This suggests that telomere length may identify subjects at increased risk of AD. Thus, we investigated the associations of peripheral blood telomere length with amnestic mild cognitive impairment (aMCI), a putative precursor of AD, among Mayo Clinic Study of Aging participants who were prospectively followed for incident aMCI. We matched 137 incident aMCI cases (mean age 81.1… CONTINUE READING
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