Short- and Long-Term Effect of Glyceryl Trinitrate (GTN) Ointment 0.2% and 2% on Anal Canal Pressure in Patients with Chronic Anal Fissures

Abstract

Controversial data are available on the duration of action of glyceryl trinitrate after acute and chronic application on anal canal pressure. Our aim was to assess the effect of glyceryl trinitrate at 0.2% and 2% on anal canal pressure before and after eight weeks of treatment. Anal canal pressure was evaluated in 12 patients with chronic anal fissures with… (More)
DOI: 10.1023/A:1005682707182

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