Short-Term Exposure to Waterpipe/Hookah Smoke Triggers a Hyperactive Platelet Activation State and Increases the Risk of Thrombogenesis

@inproceedings{Alarabi2020ShortTermET,
  title={Short-Term Exposure to Waterpipe/Hookah Smoke Triggers a Hyperactive Platelet Activation State and Increases the Risk of Thrombogenesis},
  author={Ahmed B. Alarabi and Zubair A. Karim and Jean E Montes Ramirez and Keziah R. Hernandez and Patricia A Lozano and Jos{\'e} O. Rivera and Fatima Z. Alshbool and Fadi T. Khasawneh},
  booktitle={Arteriosclerosis, thrombosis, and vascular biology},
  year={2020}
}
Supplemental Digital Content is available in the text. Objective: Cardiovascular disease is a major public health problem. Among cardiovascular disease’s risk factors, tobacco smoking is considered the single most preventable cause of death, with thrombosis being the main mechanism of cardiovascular disease mortality in smokers. While tobacco smoking has been on the decline, the use of waterpipes/hookah has been rising, mainly due to the perception that they are less harmful than regular… 
4 Citations
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It is document—for the first time—that short-term exposure to the JUUL e-cigarette increases the risk of thrombotic events, in part by modulating platelet function, such as aggregation and secretion, in mice.
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It was found that WPS was able to negatively affect the oxidative stress and inflammatory biomarkers in mice, and increased the levels of Tumor necrosis factor-α and 8-isoprostane, and DNA damage in mice lung homogenates.

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