Short-Term Effects of Rhythmic Sensory Stimulation in Alzheimer's Disease: An Exploratory Pilot Study.
@article{ClementsCorts2016ShortTermEO, title={Short-Term Effects of Rhythmic Sensory Stimulation in Alzheimer's Disease: An Exploratory Pilot Study.}, author={Amy Clements-Cort{\'e}s and Heidi Ahonen and Michael Evans and Morris Freedman and Lee R Bartel}, journal={Journal of Alzheimer's disease : JAD}, year={2016}, volume={52 2}, pages={ 651-60 } }
This study assessed the effect of stimulating the somatosensory system of Alzheimer's disease (AD) patients at three stages of their illness with 40 Hz sound. In this AB cross-over study design, 18 participants (6 mild, 6 moderate, 6 severe) each participated in 13 sessions: one intake and 12 treatment. Treatment A consisted of 40 Hz sound stimulation and Treatment B consisted of visual stimulation using DVDs, each provided twice a week over 6 weeks for a total of 6 times per treatment. Outcome…
43 Citations
Investigating the Effects of Auditory and Vibrotactile Rhythmic Sensory Stimulation on Depression: An EEG Pilot Study
- Psychology, MedicineCureus
- 2022
Improvements in MADRS scores after rhythmic sensory stimulation (RSS) were accompanied by an increase in alpha power in the occipital region and an increased in gamma in the prefrontal region, thus suggesting treatment effects on cortical activity in depression.
Gamma Entrainment in a Large Retrospective Cohort: Implications for Photic Stimulation Therapy for Alzheimer's Disease.
- MedicineJournal of Alzheimer's disease : JAD
- 2020
There is a significant effect of age on induced gamma activity, but advanced age does not fundamentally change the behavior of the response in either magnitude or spatial distribution.
Long-Term Multi-Sensory Gamma Stimulation of Dementia Patients: A Case Series Report
- Medicine, PsychologyInternational journal of environmental research and public health
- 2022
This study reports on three case studies where the use of gamma stimulation over one year contributed to maintenance of cognition and increases in mood for participants with Alzheimer’s disease or mild cognitive impairment.
An update on the use of gamma (multi)sensory stimulation for Alzheimer’s disease treatment
- BiologyFrontiers in Aging Neuroscience
- 2022
The available findings suggest its feasibility for the treatment of AD, and the need for further research for its development as a disease-modifying non-pharmacological intervention is emphasized.
The Effect of Deep Micro Vibrotactile Stimulation on Cognitive Function of Mild Cognitive Impairment and Mild Dementia
- Medicine, PsychologyInternational journal of environmental research and public health
- 2022
The findings suggest that 15–40 Hz DMV stimulation is might be effective for improving the cognitive functions in elderly people with dementia.
Benefits in Alzheimer's Disease of Sensory and Multisensory Stimulation.
- Psychology, BiologyJournal of Alzheimer's disease : JAD
- 2021
Results show sensory stimulations can effectively ameliorate the pathology of AD, arouse memory, and improve cognition and behaviors, and its potential mechanism and stimulation parameters need to be explored and improved.
Randomized Controlled Trial of Multi-Component Cognitive Stimulation Therapy (SADEM) in Community-Dwelling Demented Adults.
- Psychology, MedicineJournal of Alzheimer's disease : JAD
- 2020
The multicomponent intervention tested had positive effects on cognitive and behavioral functions and daily life activities in people with mild stage dementia, delaying progression for at least two years.
Sensory stimulation programs in dementia: a systematic review of methods and effectiveness
- Psychology, MedicineExpert review of neurotherapeutics
- 2020
This review weakly supports sensory stimulation in dementia, providing useful information for rehabilitation and future investigations, and a lack of consensus regarding frequency, duration, and number of sessions.
40 Hz acoustic stimulation decreases amyloid beta and modulates brain rhythms in a mouse model of Alzheimer’s disease
- BiologybioRxiv
- 2018
It is found that acoustic stimulation at 40Hz can reduce Aβ in the brain and restore the gamma band oscillations and the frontoparietal connectivity in a mouse model of AD.
Title Gamma band neural stimulation in humans and the promise ofa new modality to prevent and treat Alzheimer ' s disease
- Biology
- 2019
The use of a therapy based on modulation of gamma neuronal activity represents a novel non-invasive, non-pharmacological approach to AD that shows good signs of efficacy and may represent an important option for treating AD in the future.
References
SHOWING 1-10 OF 56 REFERENCES
Improved language performance in Alzheimer disease following brain stimulation
- PsychologyJournal of Neurology, Neurosurgery & Psychiatry
- 2010
Rhythmic rTMS, in conjunction with other therapeutic interventions, may represent a novel approach to the treatment of language dysfunction in AD patients.
Enhanced magnetic auditory steady-state response in early Alzheimer’s disease
- Biology, PsychologyClinical Neurophysiology
- 2006
Increased EEG gamma band activity in Alzheimer’s disease and mild cognitive impairment
- Psychology, BiologyJournal of Neural Transmission
- 2008
The results suggest that elevated GBP is a reproducible and sensitive measure for cognitive dysfunction in AD in comparison with MCI and controls and the overall TRR was high.
Discrimination of Alzheimer's disease and mild cognitive impairment by equivalent EEG sources: a cross-sectional and longitudinal study
- Psychology, MedicineClinical Neurophysiology
- 2000
Does brain ability to synchronize with 40 Hz auditory stimulation change with age?
- Medicine, PsychologyActa neurobiologiae experimentalis
- 2013
The current results suggest that the ability to synchronize to high frequency external stimulation diminishes with age, which should be taken into account when ASSRs are used in clinical practice, comparing patients and healthy subjects.
Nonpharmacological Therapies in Alzheimer’s Disease: A Systematic Review of Efficacy
- Psychology, MedicineDementia and Geriatric Cognitive Disorders
- 2010
NPTs emerge as a useful, versatile and potentially cost-effective approach to improve outcomes and QoL in ADRD for both the PWD and CG.
Nonpharmacological Treatment of Alzheimer Disease
- Psychology, MedicineCanadian journal of psychiatry. Revue canadienne de psychiatrie
- 2011
There is evidence from a modest number of well-conducted randomized controlled trials (RCTs) that various nonpharmacological approaches, including cognitive training, cognitive rehabilitation, and cognitive stimulation therapy (CST), confer modest but significant benefits in the treatment of cognitive symptoms in people with AD.
EEG dynamics in patients with Alzheimer's disease
- Psychology, BiologyClinical Neurophysiology
- 2004
Effects of a low-frequency sound wave therapy programme on functional capacity, blood circulation and bone metabolism in frail old men and women
- MedicineClinical rehabilitation
- 2009
Low-frequency sound wave therapy may have the potential to promote well-being of frail elderly subjects via improved functional capacity, especially in subjects who are too frail to undertake exercise.
Hippocampal oscillatory activity in Alzheimer's disease: toward the identification of early biomarkers?
- Biology, PsychologyAging and disease
- 2013
The concept according to which the subtle changes in theta and gamma rhythms might occur during the very first stages of AD are introduced and thus could be used as a possible predictor for the disease.