Short Psychodynamic Supportive Psychotherapy, antidepressants, and their combination in the treatment of major depression: a mega‐analysis based on three Randomized Clinical Trials

@article{deMaat2008ShortPS,
  title={Short Psychodynamic Supportive Psychotherapy, antidepressants, and their combination in the treatment of major depression: a mega‐analysis based on three Randomized Clinical Trials},
  author={Saskia C M de Maat and Jack J. M. Dekker and Robert A. Schoevers and Gerda van Aalst and Cecile Gijsbers-van Wijk and Mari{\"e}lle Hendriksen and Simone Kool and Jaap Peen and Rien Van and Frans de Jonghe},
  journal={Depression and Anxiety},
  year={2008},
  volume={25}
}
The efficacy of Short Psychodynamic Supportive Psychotherapy (SPSP) has not yet been compared with pharmacotherapy. A mega‐analysis based on three original Randomized Clinical Trials (RCTs) was performed. Patients with (mild to moderate) major depressive disorder were randomized in (24 weeks) SPSP (n = 97), pharmacotherapy (n = 45), or their combination (n = 171). Efficacy was assessed by the Hamilton Depression Rating Scale (HDRS), Clinical Global Impression of Severity and of Improvement (CGI… 
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